Biomarkers of ABCA-1 Functions in Alzheimer’s Disease

  • We hypothesize that this functional capacity of CSF can serve as a biomarker providing unique information regarding pathophysiology of AD and identifying participants that could be benefit from ABCA1 agonist treatments.
  • In this project, we propose that ABCA1 mediated cholesterol efflux capacity and HDL particle numbers in CSF are novel and informative AD biomarkers to guide future therapies
  • Project Funding: Biomarkers of ABCA-1 Functions in Alzheimer’s Disease.